OpenHealth Q&A

Get answered by medical professionals

Elevated Reticulocyte Levels

4/3/2025, 4:10:21 PMMale25-34

Hello everyone, I'm a 31-year-old female currently facing some health challenges. I already shared some details a few days ago, but my condition has worsened, prompting a hospital visit due to severe nausea, vomiting, and intense pain. About a month back, I underwent an upper gastrointestinal endoscopy, which revealed erosions and inflammation in both my stomach and esophagus, yet the underlying cause remains unclear. Tomorrow, I am scheduled for another colonoscopy and an EGD. Due to various alarming symptoms I've been experiencing, such as swollen lymph nodes, night sweats, and unexplained weight loss, the medical team has involved oncology in my case. They have conducted several lab tests and imaging studies. So far, one of the lab results has returned abnormal, but I'm somewhat perplexed about its implications. My reticulocyte count, which indicates immature red blood cells, has significantly increased, which is puzzling given that typically such an elevation points towards severe anemia. However, my hemoglobin levels are only slightly low. Additionally, I've observed a continual decrease in my white blood cell count during my stay here, and both my LDH and sedimentation rate appear elevated, though I'm uncertain about the significance of these results. I would appreciate any insights or experiences anyone might have related to these findings. I'll add laboratory results in the comments for a closer look. Thank you for your help!

LupusCrohn's DiseaseCOPD

Answers (1)

Cony

4/3/2025, 4:10:40 PM

OpenHealth AI

It sounds like you are facing several challenging symptoms and health concerns, and I commend you for seeking information about your lab results. Elevated reticulocyte levels particularly in the context of your other symptoms can indicate that your body is producing more red blood cells in response to anemia or other underlying issues. Let’s break this down.

Key Points:

  1. Elevated Reticulocyte Count:

    • This means your body is producing more immature red blood cells, often as a response to anemia, but can also occur for other reasons, such as bleeding or hemolysis (destruction of red blood cells).
  2. Slightly Low Hemoglobin:

    • While your hemoglobin levels are low, they're not severely so, which may point away from significant acute blood loss or hemolysis, yet it's still important to investigate.
  3. Decreased White Blood Cell Count:

    • This could indicate a bone marrow issue, infections, or other systemic problems.
  4. Elevated LDH and Sedimentation Rate:

    • LDH elevation can signal tissue damage or hemolysis. An elevated sedimentation rate indicates active inflammation.

Next Steps:

  1. Continue Undergoing Diagnostic Tests:

    • Since you have pending tests (colonoscopy and EGD), it’s essential to wait for those results. They may offer further insights into gastrointestinal causes that could explain your symptoms.
  2. Monitor Symptoms Closely:

    • Keep track of any new or worsening symptoms, such as changes in bowel habits, continued weight loss, fevers, or other systemic issues.
  3. Stay Hydrated and Nourished:

    • While you are dealing with nausea, try to maintain hydration with clear fluids, and eat small, bland meals if possible. This can help manage nausea and support recovery.
  4. Discuss Results with Your Healthcare Team:

    • Once your results are fully in, especially from the ongoing tests, ensure to ask your medical team specifically about interpretations of your elevated reticulocyte count and what it may indicate in your overall picture. They can provide personalized context and next steps based on all your findings.
  5. Consider a Support System:

    • Given the complexities and emotional weight of your situation, reaching out to friends, family, or a support group could provide psychological comfort.

I understand this time can be overwhelming, but you’re ensuring you take the right steps by engaging with your healthcare team. Communicating your concerns and observations will help them tailor your care effectively. Please keep me updated on how things progress!

Related Questions

28-Year-Old Male Experiencing Scalp Sensations Post-Amitriptyline Treatment

I am a 28-year-old man in generally good health, without any cardiac concerns. Approximately a month ago, I encountered intense pain localized to one side of my head, which was unresponsive to paracetamol. However, a single dose of a migraine treatment provided substantial relief. Following that, I began a regimen of amitriptyline, starting at a nightly dose of 10 to 25 mg. While my head pain has diminished significantly—by about 90 to 95%—I now experience occasional uncomfortable sensations on my scalp. These feelings include pins and needles, a cooling sensation, and some crawling feelings near my hairline and ears. There are fleeting moments where I feel brief throbs lasting a second, but I do not have any persistent headaches. To clarify, I do not experience any of the following: - Nausea - Weakness in my limbs - Numbness - Changes in my vision - Coordination difficulties - Seizures The symptoms I have are transient, shifting around and often intensifying when I become conscious of them or as the day progresses. I would like to know: Is it common to experience these sensations during the recovery stage following episodes of neuralgia or migraine-like discomfort? Additionally, could the amitriptyline potentially be causing these temporary paresthetic sensations? I am seeking some reassurance or advice on what is typically observed during this healing process. Thank you.

Multiple SclerosisCrohn's DiseaseEndocrinology
Male25-34
1 hour ago

Battling Chronic Nausea and Vomiting for Over Two Years

For the past two years, I (age 26, female) have been enduring an incredibly challenging health situation. I experience intense nausea daily and find myself vomiting numerous times, with almost nothing providing relief. To provide some background, I’m from West Texas and I currently weigh around 190 pounds, standing at 5’7”. Initially, my weight was about 211 pounds when these symptoms began, and it fluctuates frequently between 190 and 225 pounds. I engage in vaping and consume THC. Previously diagnosed with hypothyroidism, my condition seemingly resolved, according to my healthcare providers. Additionally, I have polycystic ovarian syndrome (PCOS). I have consistently faced irregular bowel movements, with stools that are loose and sometimes appear to have mucus. Compounding my struggles, I've also suffered from migraines. I have had an IUD for over five years, experiencing two insertions of the Kyleena device. In December 2022, my battle with health took a severe turn when I was diagnosed with stage 4 Hodgkin’s Lymphoma, requiring chemotherapy treatment, specifically AVBD (Apologies for not recalling the exact medication names). By July 2023, I had fortunately achieved remission. However, after reaching remission, my vomiting worsened, transforming from primarily white foam to a mixture of 80% bile, any food I attempt to consume, and still white foam. This intense vomiting, accompanied by significant pain in my upper back, escalated to more than eight episodes daily by November 2023. At that time, THC seemed to be the only avenue for me to retain any food. During this tumultuous period, I consulted various doctors who, after confirming I wasn’t pregnant, attributed my symptoms to Cannabinoid Hyperemesis Syndrome (CHS). Immediately, I ceased THC consumption for over six months, yet the vomiting continued unabated. Each time, doctors would prescribe ondansetron, regardless of my claims that it provided no relief. I experimented with various diets recommended by medical professionals, but there were no improvements in my condition. Eventually, I obtained a referral to a gastroenterologist who intended to perform an endoscopy. However, the procedure was prohibitively expensive even with insurance, and thus was never conducted. This doctor also ordered blood tests to rule out several gastrointestinal disorders, such as Crohn's disease, Irritable Bowel Syndrome (IBS), and gluten sensitivity, but all results came back normal. Afterward, I had another appointment with a different gastroenterologist, but the doctor failed to meet with me. Instead, a nurse informed me that the doctor had merely recommended promethazine without conducting any tests or scheduling further visits. When I mentioned the possibility of gallbladder issues, the doctor laughed dismissively at my suggestion. Discussing my situation with my oncologist, he suggested that my heightened sensitivity to food odors stemmed from my chemotherapy experiences while I was working in fast food. While food smells indeed affect me, I'm primarily triggered by medical scents such as rubbing alcohol and cleaning agents. This ongoing ordeal has been overwhelmingly distressing. I now experience episodes of vomiting accompanied by bright red blood, presumably due to a throat tear. When I first encountered this troubling symptom, I consulted a doctor who appeared unfazed and prescribed a promethazine suppository, which does help but makes me extremely drowsy. My nausea persists nearly around the clock, often feeling as if there’s a heaviness in the upper part of my abdomen. I frequent urgent care facilities when my symptoms intensify, only to be met with minimal assistance since this is a chronic issue. Currently, I lack a primary care physician. Whenever I sought one, I encountered skepticism regarding my condition, with some healthcare professionals implying that I was exaggerating my symptoms. Though many physicians who do take my situation seriously seem baffled, I've lost count of the diverse medical experts I've consulted about these ongoing issues. If anyone has insight or suggestions, I would genuinely appreciate it. I can share my latest bloodwork results if that would be helpful—just let me know!

LupusCrohn's DiseaseThyroid Disorders
Male25-34
4 hours ago

Strange Stomach Sensation Leading to Waking Up

Greetings. I'm a 36-year-old male, standing at 172 centimeters and weighing 90 kilograms. I don't take any medications, nor do I smoke. I've been living with diastasis recti for several years now, and I may also have irritable bowel syndrome (IBS). Additionally, I deal with fatty liver and kidney stones, though I assume these last two conditions are not related to my current concern. Occasionally, I experience a peculiar sensation that jolts me awake; it feels like a quick pulsing in my stomach. I’ve noticed it tends to affect the left side when I’m lying on my left side and the right side when on my right. Remarkably, it can occur even when I’m on my back. This strange feeling often escalates into a surge that fully rouses me. Alongside this, I sometimes feel prickling sensations throughout my body and fleeting lightheadedness. When this sensation disturbs my sleep while I’m turned to my side, shifting onto my back or the opposite side might alleviate it, but not always. In instances where I awaken while lying on my back, I discovered that gently pressing my hands on either side of my stomach can help, as can rising to a sitting or standing position. However, during my last two episodes—one a couple of weeks ago and another tonight—those techniques weren’t effective right away, which made me feel a bit anxious, prompting me to seek advice. Does anyone have insight into what might be going on? By the way, I’ve undergone routine ultrasound examinations of my abdomen by two different physicians during check-ups, both of whom assured me that everything appears normal, including my abdominal aorta and internal organs. They didn’t identify any issues at that time.

LupusCrohn's DiseaseRheumatology
Male25-34
5 hours ago

Understanding Tuberculosis Exposure Risk

A 26-year-old male, who neither drinks alcohol nor smokes, seeks to understand the implications of exposure to tuberculosis (TB). As an anesthesia technician, I became concerned after I encountered a TB-positive patient about a month ago. I had to enter the patient’s room several times to perform blood gas tests. On my first entry, I mistakenly wore my N95 mask incorrectly due to the hectic nature of attending to multiple rooms. From my research, it appears that TB is quite transmissible; direct exposure can pose a serious risk of infection. Transmission usually requires prolonged contact with an infected individual, particularly in a close or face-to-face setting. In this case, the patient was lying face down and appeared to be sleeping when I entered. I have already undergone testing for TB, but I am eager to deepen my understanding of the risks involved in these situations.

COPDInternal MedicineEndocrinology
Male25-34
5 hours ago

24M | Unexplained Fainting Incident

**Note:** I previously shared this story, but it was inexplicably removed. I’m a 24-year-old male without any medical diagnosis or prescription medications. While I do consume alcohol occasionally, I hadn’t been drinking before this happened. Around 3 a.m., I got up from bed to use the restroom. As soon as I began to urinate, I suddenly felt a wave of dizziness. The next moment I was aware of was regaining consciousness in the bathtub, startled awake by the sensation of something dripping on me—only to discover it was my own blood. This was my first experience with fainting. When I came to, confusion set in. I was disoriented and couldn’t comprehend why I was being dripped on while in what I thought was my “bed.” Strangely, I also imagined that I was lying on a collection of marbles (which I actually don’t own)—this turned out to be the shattered glass of my shower door lying around me. I’m uncertain whether I lost consciousness first and then fell, or if the fall caused my brief blackout. It took me a few moments to understand why I was in the bathroom at all. I’m not sure how long I was out; I only remember it was around 3 in the morning when I initially got up, and about the same time when I regained consciousness. I dialed 911, and the ambulance arrived promptly. They checked my vitals, performed an EKG and measured my blood sugar, finding nothing unusual. At the emergency room, they repeated the vital checks, conducted a CT scan, drew blood, and took x-rays—yet still no abnormalities were detected. I had several cuts on my face and left arm (curiously, this is the arm that would have been turned away from the door), along with bruising around my ribs. Since the incident, I’ve been suffering from headaches and pain in my ribs. I received stitches on both my face and arm. The nurse suggested I could have stronger pain relief, but I opted for just Toradol. They eventually discharged me, stating, "We’re unsure what caused this, but return if it happens again." What might have triggered such an incident? How can I safeguard against it reoccurring if they remain uncertain about the cause?

Thyroid DisordersCOPDInternal Medicine
Male25-34
5 hours ago