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Struggling with Treatment-Resistant Depression?

4/3/2025, 3:10:26 PMMale25-34

Hello all, I’m a 30-year-old female who received a diagnosis of depression and anxiety in 2021. After my diagnosis, I began treatment immediately and have also been attending therapy sessions. Now, as a resident, I find myself facing significant challenges. Unfortunately, my depression seems to have intensified. I have tried approximately nine different antidepressants along with an antipsychotic, yet I haven’t experienced any improvements. This situation is now impacting my performance during rotations, making it hard for me to concentrate on tasks. It feels like I’m losing interest in everything, and I constantly feel exhausted. Most days, I struggle to rise from bed, and I find it difficult to focus on notes or projects. Conversations with my supervisors often seem to go in one ear and out the other, leaving me unable to retain information. I sense that my options are quickly dwindling. I met with a counseling resident two weeks ago who advised me to keep pursuing treatment, especially after I began to share some passive thoughts of self-harm. Until this point, most of my meetings with my psychiatrist have been conducted virtually. However, during my last visit in person, my psychiatrist began to assess me for bipolar disorder. After determining that I did not meet the criteria for that diagnosis, they suggested I had exhausted all the recommended depression treatments. They encouraged me to find an in-person psychiatrist for further evaluation. But I can’t help but wonder: what can they do in person that isn’t possible through telehealth? I’m feeling overwhelmed. What pathways are available to me? I’m at my wit's end and desperately want to escape this feeling.

TherapyAnxietyDepression

Answers (1)

Cony

4/3/2025, 3:10:52 PM

OpenHealth AI

I'm really sorry to hear that you're feeling this way. It's clear that you've been through a lot, and navigating treatment-resistant depression can feel incredibly isolating and frustrating. Let's break down your situation and explore actionable steps that might help you find relief.

Main Points:

  1. You've tried multiple treatments without improvement, which is understandably distressing.
  2. Personal interaction with a psychiatrist may offer new perspectives and options for treatment.
  3. There are alternative therapies and strategies that can be explored beyond medication.

Explanation:

Treatment-resistant depression means that standard treatments, like antidepressants and therapy, haven't worked for you yet. It's important to keep in mind that you're not alone—many people struggle to find effective treatment. In-person evaluations can provide a more comprehensive understanding of your challenges, as they allow for a deeper assessment of your mood, behavior, and any potential physical issues contributing to your symptoms.

Next Steps:

  1. Find an In-Person Psychiatrist: Seek a clinician who specializes in treatment-resistant depression. They may suggest advanced therapies such as:

    • Transcranial Magnetic Stimulation (TMS): A non-invasive method that may help improve symptoms.
    • Ketamine infusions: Some patients have found relief with this treatment.
    • Electroconvulsive Therapy (ECT): Often effective for severe depression that hasn't responded to other treatments.
  2. Enhance Therapy Sessions: If you're currently in therapy, consider discussing medication management regularly. In-person therapy can also provide a stronger support system and more intensive therapy options.

  3. Prioritize Self-Care: Focus on small, manageable daily activities that promote your well-being, such as:

    • Setting a daily routine with specific times for waking, meals, and rest.
    • Incorporating gentle physical activity, even short walks if possible.
    • Practicing mindfulness or relaxation techniques that may help reduce anxiety.
  4. Build Your Support System: Talk to trusted friends or family about your feelings. Sometimes sharing your experience can alleviate some burden and provide the support you need.

  5. Keep Communication Open: With your psychiatrist, ensure you communicate any worsening symptoms or new concerns you have, including any thoughts of self-harm. This is crucial for tailoring your ongoing care.

Take things one step at a time, and remember that it's okay to seek help. You're taking an important step by reaching out and looking for pathways to better manage your feelings. If you need more specific information or additional resources, feel free to ask.

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