Questions Regarding Recent Blood Test Results
Hello everyone, To give you some background, I am a 42-year-old woman who was diagnosed with pernicious anemia over ten years ago. I receive monthly B12 injections, and while my B12 levels consistently come back normal, other tests continue to show signs of anemia. Recently, I encountered some unusual findings in my lab results: - My white blood cell count (WBC) was lower than ever at 3.89. - My red blood cell count (RBC) remains consistently low at 3.36, with my MCV (mean corpuscular volume) at 105 and MCH (mean corpuscular hemoglobin) at 35.4, both of which have been gradually worsening each year. - The RDW-SD (red cell distribution width-standard deviation) was elevated at 47. - Additionally, my basophil count was high (1.3), while my absolute lymphocyte count fell to a low of 1.14. - My anion gap was also recorded as low (8). - My cholesterol levels were concerning at 226, although my HDL was exceptionally high, yielding a favorable ratio of 2.1. All other parameters, including my A1C and fasting triglycerides, returned to normal ranges. Moreover, I recently underwent a diagnostic mammogram due to the detection of a cluster of calcifications, but thankfully, the results came back normal. I would greatly appreciate any insights or advice on my situation. While I’ve tried to contact my doctor, I'm feeling anxious as I await their response. Thank you for your help!
Answers (1)
4/2/2025, 6:00:58 PM
OpenHealth AI
It sounds like you're dealing with several complex lab results that are causing you concern, and it's understandable to feel anxious while waiting for your doctor's feedback. Here’s a breakdown of the key points and some actionable steps you can take in the meantime.
Key Points
- Ongoing Anemia: Your red blood cell count is low despite monthly B12 injections for pernicious anemia.
- WBC and Lymphocyte Concerns: Your white blood cell count is low, with a concerning drop in lymphocytes, which may suggest some underlying issues.
- High Cholesterol: Although your total cholesterol is elevated, your HDL is in a healthy range.
- Normal Mammogram: This is a positive finding and a relief amidst your other concerns.
Explanation
Your ongoing low red blood cell count, along with the values of MCV and MCH, indicates a type of anemia that may be macrocytic (larger cells) despite having normal B12 levels. The altered white blood cell counts could indicate a potential bone marrow issue or another condition requiring further diagnosis. It's important to stay vigilant regarding anemia's causes, such as nutritional deficiencies beyond B12 (like folate), bone marrow disorders, or chronic diseases.
Next Steps
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Monitor Symptoms: Keep track of any symptoms like fatigue, weakness, or unusual infections, and note any changes. Documenting your symptoms can be helpful for your doctor to understand your situation fully.
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Dietary Review: Since you have pernicious anemia, ensure you are getting adequate folate and iron in your diet. Foods rich in vitamin B9 (like leafy greens, legumes) and iron (like red meat, beans, and fortified cereals) can be beneficial.
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Hydration and Lifestyle: Stay well-hydrated and maintain a balanced diet to support overall health, which can also help regulate your blood levels.
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Stay Proactive with Follow-Ups: While your doctor will provide the most accurate guidance, don’t hesitate to reach out for results of any follow-up tests, or to call back if you don’t hear from them in a timely manner.
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Focus on Cholesterol Management: If you haven’t already, consider working on lifestyle changes that can support lower cholesterol levels, such as regular physical activity and a heart-healthy diet rich in fruits, vegetables, whole grains, and healthy fats.
It's completely normal to feel anxious when awaiting medical advice, but you are taking a proactive approach by seeking information and support. Please remember that your healthcare team will provide the most personalized insights regarding these results. If any symptoms become severe or worrisome, consider seeking immediate care.
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