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Should I Be Concerned About My High ALP and ALT Levels?

4/2/2025, 4:10:23 PMMale25-34

I am a 32-year-old woman weighing 120 pounds, with a medical history that includes dysautonomia. At present, I'm receiving intravenous vitamins twice a week to manage my hypovolemic postural orthostatic tachycardia syndrome (POTS). I find myself puzzled by the results of my laboratory tests, and it appears that there hasn’t been much follow-up regarding them. There haven't been any repeat tests scheduled. My recent abdominal ultrasound showed no significant findings, and I have tested negative for both autoimmune hepatitis and primary biliary cholangitis. What are your thoughts on this situation? Would it be advisable for me to request another round of lab tests? A rheumatologist has suggested that I should consult a liver specialist, but there is an extensive wait time for such appointments.

Multiple SclerosisLupusThyroid Disorders

Answers (1)

Cony

4/2/2025, 4:10:41 PM

OpenHealth AI

High ALP (alkaline phosphatase) and ALT (alanine aminotransferase) levels can indicate liver or bone issues, but it’s great that you’re actively engaging with your health and concerned about your lab results. Given your existing health conditions like POTS and the negative tests for autoimmune liver diseases, it's understandable to want clarity on your situation.

Explanation

  • ALP and ALT Levels: Elevated ALP could suggest issues related to the liver, bile ducts, or bones. High ALT typically indicates liver cell damage. Since your ultrasound and tests for autoimmune conditions came back normal, it's important to look into potential non-liver-related causes or consider lifestyle factors like medication effects, diet, or stress which could affect liver enzymes.

  • Dysautonomia and Nutrient Absorption: Your condition might affect blood flow and how your body absorbs nutrients, which can indirectly influence liver function and enzymes.

Next Steps

  1. Request a Follow-Up Lab Test: Given your concerns and symptoms, consider requesting a follow-up liver panel to monitor your ALP and ALT levels. This can help establish any trends or changes.

  2. Keep a Symptom Diary: Track any associated symptoms (fatigue, jaundice, changes in appetite) and your current medications or supplements. This information can be valuable for your healthcare provider.

  3. Nutritional Considerations: Focus on a balanced diet rich in fruits, vegetables, and whole grains. Ensure adequate hydration, especially as you manage POTS. Heavy alcohol or processed food intake can contribute to liver stress; if applicable, consider moderating these.

  4. Discuss Concerns with Your Current Provider: If there’s a long wait for the liver specialist, have an open conversation with your current healthcare provider about your test results and ask if there are alternative testing or specialists available to expedite your care.

Reassurance

Be proactive about your health, but also remember that many causes for elevated liver enzymes can be benign and reversible. Stay engaged with your healthcare team, and your efforts to follow up will greatly assist in managing your health effectively. If symptoms worsen, don’t hesitate to seek immediate medical attention.

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