Understanding My Blood Test Results: Concerns About Leukaemia
A woman in her late thirties has recently had some troubling blood test outcomes that have raised significant worry, especially as she anticipates a follow-up appointment. The most alarming aspect is the noticeably elevated LD level alongside abnormalities in RCC, MCV, and MCH. Furthermore, the ESR and CRP values are also contributing to her anxiety. She has been experiencing fatigue and has noticed an increase in bruising. Despite having normal platelet counts, she is questioning whether it is irrational to consider a severe condition such as leukaemia as a potential cause. It's worth noting that sometimes medical signs do not align perfectly with clinical conditions. For a bit of background, she has been living with Coeliac disease, diagnosed through an endoscopy 16 months ago, and has been diligent in maintaining a gluten-free diet since that time. In addition, she underwent a hemi-thyroidectomy last October due to a multi-nodular goiter; fortunately, no cancer was found, and it was confirmed that there were no autoimmune elements. Her endocrinologist has indicated that her thyroid levels are acceptable and that she is not hypoactive, which rules out those symptoms as a possible explanation for her recent test results. Despite adhering to a gluten-free regimen, she continues to deal with gastrointestinal issues. Interestingly, past blood tests indicated that she probably had coeliac disease for at least ten years before her formal diagnosis. Historically, her LD, RCC, MCV, and MCH values have always been within the normal range throughout numerous tests conducted over the years due to chronic health issues. Below are her blood test findings; she refrained from listing results that fell within normal limits, except for a potentially relevant thyroid marker, as the slightly elevated TSH might offer some additional insight. Any thoughts or opinions would be highly valued, as she wishes to brace herself for any forthcoming examinations. **Complete Blood Count:** - RCC: 3.1 (normal range 3.6-5.2) - MCV: 108 (normal range 80-98) - MCH: 39 (normal range 27-35) - All other results within normal limits **CRP:** 11 (normal range 0-6) **ESR:** 31 (normal range 1-20) **Comprehensive Liver Function Tests:** - Sodium: 136 (normal range 137-147) - Bicarb: 22 (normal range 25-33) - LD: 746 (normal range 80-250) - All other extensive liver function parameters within normal limits. **Iron Studies:** All values are normal. **Diabetes Panel:** All values are normal. **Thyroid Studies:** - TSH: 5.4 (normal range 0.5-4) - Free T4: 13 (normal range 10-20) - Free T3: 4.8 (normal range 2.8-6.8)
Answers (1)
3/31/2025, 1:30:50 PM
OpenHealth AI
Elevated LD levels and abnormalities in blood tests can understandably raise concerns, especially when paired with symptoms like fatigue and increased bruising. It's important to approach this situation with a clear mind, as many factors could contribute to your results, especially considering your history of Coeliac disease.
Explanation:
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Elevated LD (Lactate Dehydrogenase): This enzyme can be elevated due to a variety of reasons, including liver disease, hemolysis (destruction of red blood cells), or other inflammatory conditions. It doesn't specifically indicate leukaemia but can be a signal that something is affecting your body.
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RCC, MCV, MCH Abnormalities:
- Your low RCC (Red Cell Count) suggests a possible mild anemia, which can be caused by various factors, including nutritional deficiencies (even with Coeliac disease, some nutrients might still be lacking).
- High MCV (Mean Corpuscular Volume) and MCH (Mean Corpuscular Hemoglobin) can indicate macrocytic anemia, often due to vitamin B12 or folate deficiency.
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ESR and CRP: Elevated levels of these inflammatory markers indicate that there is some ongoing inflammation, which can be caused by several conditions, not necessarily leukaemia.
Next Steps:
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Monitor Symptoms: Keep a detailed log of any new or worsening symptoms, including fatigue, bruising, or gastrointestinal issues. This will help your healthcare provider understand your changes better.
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Nutrition Review: Ensure your gluten-free diet is nutritionally balanced. Consider consulting a dietitian to review your diet, as deficiencies in B vitamins or iron could contribute to your symptoms and blood test results.
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Follow-Up with Your Doctor: Prepare for your upcoming appointment by gathering all test results and symptoms. Discuss your concerns openly and ask about specific follow-up tests that may rule out conditions, including vitamin levels and further testing for any underlying issues related to your Coeliac disease.
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Stay Informed: While it’s natural to worry, try to focus on preparing for your appointment rather than panic. Ask your doctor directly about the likelihood of leukaemia based on your tests and symptoms.
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Take Care of Yourself: Prioritize rest and manageable stress-reducing activities as you navigate this period.
Approach your follow-up appointment with the goal of understanding and addressing your test results comprehensively. Maintaining an open dialogue with your healthcare team will help ensure you receive the care you need. Stay positive, and remember that your symptoms may have several explanations, many of which are manageable.
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