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Developing a Rash After Initiating Methylprednisone

3/30/2025, 5:50:17 PMMale25-34

I am a 23-year-old woman, measuring 5 feet 4 inches and weighing 134 pounds. I do not smoke and take several medications, including levothyroxine, topiramate, and vitamin D3, in addition to starting methylprednisone recently. Last weekend, I experienced an allergic reaction to a deodorant, which resulted in blisters appearing in my armpit. Following this incident, I visited an urgent care facility where I was prescribed prednisone. I commenced this treatment on Friday morning, marking the start of my third day out of a six-day course. That same evening, I noticed the emergence of a rash (details are in the comments), which initially appeared in my armpit but has since begun to spread. By now, it has advanced towards my hip on the same side as the original issue. Could this rash be a common reaction to oral steroids?

Thyroid DisordersEndocrinologyRheumatology

Answers (1)

Cony

3/30/2025, 5:50:33 PM

OpenHealth AI

It sounds like you're dealing with a concerning rash that has developed alongside your treatment with methylprednisolone. While rashes can occur for various reasons, the timing of this rash after starting the medication raises some important considerations.

Main Points:

  1. The rash may be related to an allergic reaction to the deodorant, worsening under steroid treatment.
  2. Methylprednisolone can occasionally cause skin reactions, but a rash spread beyond the original site could indicate another issue.
  3. Close monitoring and specific steps to manage symptoms are crucial.

Explanation: Methylprednisolone is a steroid that helps reduce inflammation and is commonly prescribed for allergic reactions. However, it can also lead to side effects, including skin reactions, especially if your body is reacting to other allergens. In your case, since the rash started after an allergic reaction to deodorant and coincided with the initiation of steroids, it might be a continuation of that reaction or a new one triggered by the medication.

Next Steps:

  1. Document the Rash: Take note of the appearance, size, and spread of the rash. Photographs can help you track changes if needed.
  2. Avoid Triggers: Steer clear of any known irritants, such as the deodorant that caused your initial reaction, and avoid fragrances or other potential allergens for now.
  3. Topical Treatment: If you have access to over-the-counter hydrocortisone cream, applying it to the rash may help reduce inflammation and itching. Alternatively, calamine lotion can soothe the area.
  4. Monitor Symptoms: Keep an eye on any changes in the rash and any new symptoms such as increased itching, swelling, or other areas of rashes appearing.
  5. Seek Further Help: If the rash continues to spread or you experience severe itching, pain, fever, or if you feel unwell overall, it is important to reach out to a healthcare professional for personalized advice.

I hope this helps you navigate your situation more comfortably. Take care of your skin, and be cautious about new products you use. Let me know if you have more questions or need further guidance!

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