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Interpreting C. Diff Test Results: What to Do Next?

3/29/2025, 7:00:21 PMMale25-34

After experiencing symptoms following a course of antibiotics after my surgery, my physician advised that I undergo testing for Clostridium difficile. The results are in: Antigen test - positive Toxins A and B - not present Since my doctor's office is currently closed, I’m wondering whether it’s prudent to seek advice at the emergency room or urgent care rather than hold off until Monday. Is it typical to test positive for the bacteria without the presence of toxins, or does this raise any concerns? I could use some guidance here!

Bacterial InfectionViral InfectionInfectious Disease

Answers (1)

Cony

3/29/2025, 7:00:41 PM

OpenHealth AI

You’ve done well to monitor your health and seek testing for C. difficile after experiencing symptoms. Your test results show that while the antigen test for C. difficile is positive, the toxins A and B, which are responsible for the disease symptoms, are not present. Here’s what this means for you:

Main Points:

  1. Positive Antigen Without Toxins: A positive antigen test indicates the presence of the C. difficile bacteria, but the absence of toxins suggests that you may not currently have an active infection causing symptoms.
  2. Symptoms Management: Monitor your symptoms closely, as the presence of the bacteria without the toxins often does not require urgent intervention.

Explanation:

C. difficile can sometimes be present in the gut without causing illness; this is known as colonization. It often occurs, especially after antibiotic use, when normal gut bacteria are disrupted, allowing C. difficile to grow. Since you are not showing the toxins, your body may not be experiencing an active infection, but it is still important to watch for any worsening of symptoms.

Next Steps:

  1. Monitor Symptoms: Keep track of any changes in your symptoms. If you develop severe symptoms such as high fever, severe abdominal pain, or diarrhea that becomes watery or is frequent, you should seek medical attention.
  2. Stay Hydrated: Make sure you’re drinking plenty of fluids to stay hydrated, especially if you are experiencing any gastrointestinal upset.
  3. Avoid Irritants: If you are experiencing diarrhea, try to avoid dairy products and high-fiber foods, which may irritate your gut further.
  4. Contact Your Doctor: Once your doctor's office reopens, reach out to them to discuss your results in detail and determine if further testing or treatment is necessary, especially if you have persistent or worsening symptoms.

Based on your current situation, heading to the emergency room or urgent care may not be necessary unless you experience severe symptoms. Keep calm and focus on your monitoring. If things worsen or you simply feel uncertain, don’t hesitate to seek care earlier. Let me know if you need further information!

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