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Understanding Ethyl Sulfate Results in Relation to Gastroparesis

3/27/2025, 6:20:22 PMMale25-34

At 24 years old, I am seeking clarification regarding some unexpected findings from a recent urine drug screening. My test indicated a presence of alcohol, specifically showing a positive result for ethyl sulfate, even though I haven’t consumed any alcohol lately. Interestingly, the test result was negative for ethyl glucuronide. Given my diagnosis of gastroparesis, I wonder whether this detection of alcohol could stem from the fermentation of food in my stomach. I would greatly appreciate any insights into the potential reasons behind this surprising positive alcohol test result.

Stomach PainIndigestionGastroenterology

Answers (1)

Cony

3/27/2025, 6:20:41 PM

OpenHealth AI

It’s understandable to feel concerned about unexpected lab results, especially regarding a positive alcohol test when you haven’t consumed any alcohol. Let’s clarify the situation regarding ethyl sulfate, your gastroparesis, and potential explanations for the test results.

Main Points:

  1. Ethyl Sulfate Presence: Ethyl sulfate is a metabolite of ethyl alcohol, which typically indicates alcohol consumption.
  2. Gastroparesis Effects: This condition can lead to slowed digestion, and in rare cases, fermentation of food may occur, potentially producing small amounts of alcohol.
  3. Negative Ethyl Glucuronide: This result can be significant as it often indicates recent alcohol consumption; a negative result alongside positive ethyl sulfate is unusual.

Explanation:

Ethyl sulfate can appear in urine when alcohol is present in the body. However, in individuals with gastroparesis, food may remain in the stomach longer than normal, leading to fermentation. This can happen with certain carbohydrates and sugars, potentially producing trace amounts of alcohol. While this is uncommon, your medical history suggests it might be worth considering.

The negative result for ethyl glucuronide is important; it often indicates that alcohol was not consumed in the immediate past (<1-2 days), which might conflict with the positive ethyl sulfate finding. This discrepancy suggests that a different process—like fermentation—could be at play if no recent alcohol was consumed.

Next Steps:

  1. Monitor Symptoms: Keep track of any gastrointestinal symptoms you experience, such as bloating, discomfort, or changes in digestion. This may help correlate with the test results.

  2. Review Diet: Consider the types of foods you are eating, especially those high in carbohydrates or sugars, which may ferment. If you notice symptoms after eating specific foods, it might be beneficial to adjust your diet.

  3. Hydration & Small Meals: Stay hydrated and eat smaller, more frequent meals to help manage your gastroparesis. This approach can also minimize discomfort from potential fermentation processes.

  4. Follow-Up: It may be helpful to discuss these findings with your healthcare provider. They can provide specialized insight about potential fermentation and recommend any further testing or dietary adjustments based on your condition.

Understanding your test results and how they may relate to your gastroparesis is key to managing both your health and any lingering concerns. If you have more questions or need further clarification, feel free to ask.

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