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Could My Medication Use Have Harmed My Kidneys?

3/27/2025, 3:00:37 AMMale25-34

I’m a 34-year-old female currently receiving treatment for mental health issues, with a troubling history of overdosing on a variety of medications in previous attempts to harm myself. My last incident occurred in 2022. Recently, I’ve been experiencing discomfort in my right kidney. Following this issue, a Urologist was consulted, who conducted some initial blood tests and a urinalysis. Throughout my medical history, urinalyses have consistently indicated the presence of trace blood and often trace amounts of protein. Interestingly, this latest test showed no protein present. However, I became concerned when I discovered that my estimated Glomerular Filtration Rate (eGFR) has dropped to 86, down from 111 less than a year ago. Prior to this, my eGFR had consistently remained above 100 since 2022, which raises alarms in my mind regarding potential kidney damage. In light of my struggles, I do acknowledge that I have been misusing my psychiatric medications, but my intent has not been suicidal; rather, I've been seeking relief to help with sleep. It’s also important to note that I have been consuming alcohol while on these medications. Now, I can’t help but wonder: Have my actions led to any renal impairment? The medications I have been taking include: - Abilify (injection) - Klonopin - Meclizine - Propranolol

Kidney PainUrologyNephrology

Answers (1)

Cony

3/27/2025, 3:01:02 AM

OpenHealth AI

It's understandable to be concerned about kidney health, especially given your medication history and recent changes in your eGFR. You are right to be attentive to how your medications and substance use may affect your kidneys. Let’s break down the situation and focus on what steps you can take now.

Main Points:

  1. Changes in eGFR can indicate potential kidney issues, but they aren’t always a sign of severe harm.
  2. Medication misuse, particularly combined with alcohol, can increase the risk of kidney damage.
  3. It's important to closely monitor your kidney health and make lifestyle adjustments.

Explanation:

The eGFR (Estimated Glomerular Filtration Rate) is a blood test that measures how well your kidneys filter waste. An eGFR of 86 is still within a generally acceptable range but indicates a decrease from your previous levels. It’s good that you’re paying attention to this, as it could be related to your medications or other lifestyle factors, such as alcohol use.

  • Medication Considerations: Some psychiatric medications can affect kidney function. For example, high doses of certain medications or using them in ways not prescribed can exacerbate kidney issues. Mixing medications with alcohol may also place extra stress on your kidneys.
  • Urinalysis Results: The presence of blood and protein in previous tests indicates some level of concern, so ongoing monitoring is essential.

Next Steps:

  1. Limit Alcohol: Reduce or eliminate alcohol consumption, especially when taking medications. Alcohol can interact negatively with your medications and affect kidney function.

  2. Medication Management: Review your psychiatric medication usage with your prescribing doctor, especially regarding your doses and how you take them. Being open about your struggles will help them find the best strategy for you.

  3. Hydration and Diet: Ensure you are drinking adequate water throughout the day, as dehydration can impact kidney function. Eating a balanced diet low in excessive salt and processed foods can also support kidney health.

  4. Follow-Up Tests: Continue regular check-ups with your urologist or nephrologist. They might recommend additional tests to monitor your kidney function and assess any potential damage.

  5. Symptom Monitoring: Pay attention to any symptoms like back pain, swelling, or changes in urinary habits, and report these to your healthcare provider.

Taking these steps can help manage your current concerns about kidney health while also addressing your overall well-being. If you have more questions or need further support, please feel free to ask.

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