Who Can Request an MMA Test?
It appears that many primary care physicians are hesitant to recommend the MMA test. In fact, I've encountered a physician who admitted to being unfamiliar with it altogether. For the past decade, my B12 serum levels have consistently been elevated, ranging from 1500 to 1999 pg/mL. I adhere to a plant-based diet and consume only minimal amounts of fortified foods. Five years ago, I discontinued my B12 supplements at the advice of my primary care doctor; however, my blood levels remain unusually high. This situation leads me to suspect that I might have a functional deficiency, prompting my interest in the MMA test. I am a 40-year-old female, standing at 5'5" tall and weighing 115 pounds. I do not smoke. My medical history includes asthma and persistent skin issues that resist conventional treatments, manifesting as itching, eczema, and hives. Additionally, I consistently experience low blood pressure and symptoms of POTS, such as headaches and dizziness when changing position. After meals, I also suffer from immediate bloating and occasional gastrointestinal discomfort.
Answers (1)
3/24/2025, 10:10:37 PM
OpenHealth AI
It's understandable that you're feeling concerned about your elevated B12 levels and the possibility of a functional deficiency. Your interest in the MMA (methylmalonic acid) test is a proactive step toward better understanding your health.
Main Points:
- The MMA test is typically requested in cases of suspected functional vitamin B12 deficiency, even when serum B12 levels are high.
- Your dietary habits, symptoms, and medical history warrant consideration for this test.
Explanation: MMA is a compound that can accumulate in the body when B12 levels are insufficient for proper metabolism, even if serum B12 levels are high. Given your plant-based diet, persistent symptoms, and previous experience with skin issues and gastrointestinal discomfort, pursuing the MMA test is a reasonable consideration. However, it is true that not all physicians are familiar with this test, which may lead to reluctance in recommending it.
Next Steps:
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Document Symptoms: Keep a detailed diary of your symptoms, including skin issues, gastrointestinal discomfort, and any episodes of dizziness or headaches. This can help healthcare providers understand your situation better.
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Seek a Specialist: Consider consulting with a healthcare provider specializing in nutrition or a hematologist, as they may be more familiar with vitamin B12 testing and related assessments like the MMA test.
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Request the Test: When discussing with a specialist, clearly express your concerns about your B12 levels and the potential for a functional deficiency. Request the MMA test to gain insights into your metabolic status.
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Nutritional Assessment: Discuss your plant-based diet openly with your healthcare provider. They may suggest adjustments or additional testing to evaluate your overall nutrient absorption and identify any other deficiencies that may be present.
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Lifestyle Considerations: To support your overall health, focus on a balanced diet rich in nutrients and consider options for integrating more fortified foods or discussing alternative supplementation under medical guidance.
Taking these steps can empower you to get to the bottom of your health concerns. Please let me know if you need further details or have specific questions regarding your situation.
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