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Enlargement of Lymph Nodes: Seeking Insights

3/23/2025, 2:10:22 PMMale25-34

Greetings everyone! I’m a 38-year-old female. After testing negative for all viruses, fungi, and autoimmune conditions, I want to share my experiences and see if they resonate with anyone else’s situations. Around a year and a half ago, I discovered swollen lymph nodes in my neck. An ultrasound revealed one abnormal node, prompting a referral to an ENT specialist. A subsequent CT scan indicated multiple swollen lymph nodes, although none exceeded 1.5 cm. About three months later, I consulted a hematologist/oncologist because of anemia and concerns about my lymph nodes. This doctor performed a CT scan and a bone marrow biopsy. My white blood cells typically fluctuate between 11,000 and 30,000, occasionally returning to a normal range for short periods. The bone marrow biopsy indicated low cellularity, at 30-35%. However, the doctor was cautious about diagnosing aplastic anemia since my red blood cell counts remained within the normal range. My ferritin level was recorded at 7, leading to five rounds of iron transfusions. In November, feeling quite unwell, I underwent another CT scan. While lymph nodes in levels 1 and 2 remained stable, there was slight enlargement noted in my thoracic area. Additionally, the scan revealed changes to my spinal alignment that were causing pressure on my spinal cord. Following this, my doctor recommended consultations with a rheumatologist and an allergist. In January 2025, I had an anterior cervical discectomy and fusion (ACDF) procedure for my spine. I also underwent three ANA tests, all of which returned negative results. The only abnormal finding was slightly low IgG levels. Due to sightings of atherosclerosis in the November CT, I had a carotid ultrasound, which turned out normal without any calcifications. However, they did notice that one of my lymph nodes appeared thickened, although the evaluation did not cover the entirety of my neck, just the artery. Upon my return to the hematologist, she identified enlarged lymph nodes beneath my right jaw, prompting her to arrange for a biopsy. These nodes have shown slight growth and are becoming thicker; she also noted smaller nodes surrounding my thyroid. The latest CT indicated additional small nodes in my chest. Can anyone offer guidance on what this may signify?

NumbnessNeurologyENT

Answers (1)

Cony

3/23/2025, 2:10:40 PM

OpenHealth AI

Main Points: Swollen lymph nodes have various potential causes, including infections, autoimmune conditions, or malignancies. Continuous monitoring and further investigations are essential.

Your situation involves complex medical findings, and it's understandable to seek insights given the lengthy journey you've had. Swollen lymph nodes can signify a range of conditions, from infections to more serious concerns, and the combination of your symptoms and test results can feel overwhelming.

Explanation: Lymph nodes are part of your immune system and can swell due to infections, inflammation, or other medical conditions. Given that you've been undergoing various tests with some abnormalities noted, the observation of enlarged lymph nodes may be concerning. However, factors like size (nodes below 2 cm are often considered benign), stability over time, and accompanying symptoms are essential in determining the significance.

Your hematologist's recommendation for a biopsy is an appropriate step, especially since they noticed changes in your nodes. The biopsy will provide more definitive answers. Your other test results, including the low ferritin and fluctuating white cell counts, could relate to your anemia or underlying issues that need addressing.

Next Steps:

  1. Complete the Biopsy: This is crucial for diagnosing the nature of the enlarged lymph nodes and will guide future treatment decisions.
  2. Keep Monitoring Symptoms: Track any new symptoms such as fever, weight loss, night sweats, or fatigue, and report these to your healthcare provider as they arise.
  3. Continue Iron Supplements: Ensure you're managing your anemia, especially since your ferritin was low. Follow your doctor's guidance on iron supplementation.
  4. Follow Up with Specialists: Maintain communication with both your hematologist and any new specialists, including the rheumatologist and allergist, to address all aspects of your health concerns.
  5. Be Mindful of Lifestyle Factors: Maintain a balanced diet, stay hydrated, and consider light physical activity if approved by your healthcare team, as this can support your overall health.

Navigating these concerns can be stressful, but you’re taking proactive steps by seeking advice and getting further evaluations. Stay engaged with your healthcare team for clear guidance moving forward. Let me know if you need more specific ideas or support.

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