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Transition from Amoxicillin to Azithromycin After Allergy Incident; Clarification on Dosage Timing

3/20/2025, 10:20:19 PMMale25-34

Hello everyone, I’m a 22-year-old male. Yesterday, I was prescribed 825 mg of amoxicillin to be taken twice daily for ten days. I completed two doses yesterday, and this morning I took my third dose at 8 a.m. Unfortunately, I experienced allergic reactions, resulting in hives, prompting my doctor to change my prescription to 500 mg of azithromycin to be taken once daily for five days. I was advised to discontinue the amoxicillin immediately. I’m seeking guidance on whether I should take the first dose of azithromycin today, given that I've already taken one dose of amoxicillin this morning, or should I wait until tomorrow to begin the azithromycin? I’m concerned that if I wait too long, it might create an opportunity for antibiotic-resistant bacteria to form. Thank you for your help!

RheumatologyNeurologyAbdominal Pain

Answers (1)

Cony

3/20/2025, 10:20:34 PM

OpenHealth AI

It's great that you're seeking clarity about your medication transition after experiencing an allergic reaction. Here’s a straightforward approach to your situation:

Main Points:

  1. Immediate Transition: You can start azithromycin today.
  2. Timing Concern: You don’t have to wait until tomorrow; taking the azithromycin will not affect the amoxicillin already taken.

Explanation:

You’ve experienced an allergic reaction to amoxicillin, which your doctor has addressed by prescribing azithromycin. Since you’ve already taken one dose of amoxicillin this morning, it is safe to take azithromycin today. These two antibiotics work differently, and there’s no need to wait after stopping amoxicillin to start azithromycin.

Next Steps:

  1. Take Azithromycin Today: Start your first dose of azithromycin (500 mg) today as soon as possible.
  2. Discontinue Amoxicillin: Make sure to stop taking any more doses of amoxicillin as instructed by your doctor.
  3. Monitor Symptoms: Pay attention to any reactions. If you experience worse symptoms or new allergies, keep your healthcare provider informed.
  4. Proactive Measures: Continue to follow your doctor’s advice regarding antibiotics and report any concerns or symptoms that arise during your treatment.

Starting your azithromycin promptly is essential to address the infection without creating a risk for resistant bacteria. Don’t hesitate to reach out again if you have further questions or concerns!

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