Change of Antibiotic During Treatment
(Female, 38 years old) Hello! I would appreciate some insights from fellow healthcare providers regarding a recent change in my antibiotic prescription. Initially, I was prescribed amoxicillin due to symptoms indicative of a urinary tract infection (UTI). I was taking 875 mg of amoxicillin twice daily for five days. However, a few days later, I received a call from the physician's assistant informing me that the results of my urinalysis revealed the presence of Enterobacter aerogenes and cloacae. Consequently, I've been advised to discontinue the amoxicillin and begin a course of Bactrim DS at 800 mg twice daily for five days. Is it common practice in the medical field to modify antibiotic treatment midway? Furthermore, is Bactrim appropriate for addressing infections caused by this specific bacteria? I tend to be cautious about introducing new medications and often have numerous questions regarding their use. Additionally, I am currently taking a GLP-1 medication (Wegovy); the pharmacist indicated that there should be no interactions. However, I am concerned whether the GLP-1 could potentially lead to a delayed adverse response or exacerbate any side effects associated with Bactrim?
Answers (1)
3/20/2025, 6:10:36 PM
OpenHealth AI
Main Points: It’s common for healthcare providers to adjust antibiotic treatment based on lab results, and Bactrim DS (sulfamethoxazole and trimethoprim) is generally appropriate for treating infections caused by Enterobacter aerogenes. Your concerns about potential interactions with your current medication are valid but can be addressed thoughtfully.
Explanation: When a patient’s urine test reveals a resistant bacteria like Enterobacter aerogenes, doctors often modify treatment to ensure the antibiotic is effective. Amoxicillin might not work against this specific bacteria, which is why your physician suggested switching to Bactrim DS. This antibiotic is often effective against Enterobacter species, but it’s important to complete the full course as prescribed.
Regarding your concern about the GLP-1 medication, current evidence supports that there are no major interactions between GLP-1 drugs like Wegovy and Bactrim. However, it's wise to monitor how you feel as you start the new antibiotic. Side effects can vary from person to person, and being vigilant will help you catch any potential issues early.
Next Steps:
- Start Bactrim DS: Begin your new prescription as directed, taking it with plenty of water to help prevent any possible side effects like kidney issues.
- Monitor Symptoms: Pay close attention to how your body reacts in the first few days. Look out for any side effects like rash, fever, or gastrointestinal issues, and take note of any changes in your UTI symptoms.
- Stay Hydrated: Drinking plenty of fluids can help you flush out the infection and support your kidneys while on antibiotics.
- Document Concerns: Keep a log of any side effects or concerns you have regarding your new medication and your ongoing symptoms. This will be helpful if you need to discuss anything with your healthcare provider later.
- Follow Up: If your symptoms do not improve within a few days, or if you experience severe side effects, be proactive in reaching out to your healthcare team for further guidance.
Please feel free to reach out if you have more questions or need clarification on any steps!
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