OpenHealth Q&A

Get answered by medical professionals

Rash Following Antibiotic Use: Allergic Reaction or Another Cause?

3/20/2025, 3:30:30 PMMale25-34

Hello everyone, I’m a 26-year-old woman. My daily health regimen includes taking propranolol to manage anxiety; otherwise, I don’t take any other medications. While I don't have any confirmed allergies, I suspect I might be sensitive to penicillin due to a prior experience where I developed a rash after using an antibiotic containing it, but it was never officially verified. Recently, I completed a 7-day course of trimethoprim, prescribed for a suspected urinary tract infection (accompanied by urgency and discomfort). I finished the medication on Tuesday and felt back to my usual self with no significant side effects, except for some mild nausea on the first day. However, on Wednesday morning, I woke up to discover several red raised spots on my hand. Initially, I didn’t think too much of it but later that evening, I noticed another spot on my leg. I went to bed without worrying, but this morning I found myself with numerous similar spots across my body. While most spots are slightly raised, many feel like they’re just part of my skin. The clusters are particularly concentrated on my stomach and left arm, with a prominent one on my face and additional spots on my thighs, hands, neck, and groin area—essentially, they’re everywhere. The only symptom accompanying these spots is a minor level of discomfort, but there isn’t much itching to speak of. I didn’t even realize I had a rash until I stumbled upon it and investigated further. These spots fade when I press on them. I would greatly appreciate any advice or insights, as I struggle with health anxiety and even sharing my concerns helps alleviate some stress. I’m also not very savvy with Reddit, so if there are alternative methods to provide more information, please let me know. Thank you for your time!

Skin AllergiesDrug AllergiesPet Allergies

Answers (1)

Cony

3/20/2025, 3:30:54 PM

OpenHealth AI

It sounds like you are experiencing a widespread rash after completing a course of trimethoprim, which can be concerning. Given your previous experience with penicillin and your current symptoms, it’s important to evaluate the situation carefully to determine the cause and ensure your comfort and safety.

Main Points:

  1. The rash you are seeing may be an allergic reaction to trimethoprim or another skin condition.
  2. Monitoring symptoms and taking specific actions at home will be key in managing this situation.

Explanation:

Rashes can be triggered by various factors, including medications, infections, or even environmental allergens. Since you noted an absence of itching and that the spots fade with pressure, this may suggest a mild reaction rather than an acute allergic response. However, the fact that you're experiencing a sudden onset of a widespread rash following antibiotic use warrants careful observation.

Next Steps:

  1. Monitor Your Symptoms:

    • Keep an eye on the rash. Note any changes in its appearance, such as increased redness, swelling, or other symptoms like difficulty breathing or swelling of the face. These could indicate a more serious allergic reaction.
  2. Avoid New Products:

    • Refrain from applying any new lotions, ointments, or topical treatments to the affected areas until the rash resolves.
  3. Soothing Care:

    • You can try using cool compresses on the rash to help soothe discomfort. Over-the-counter antihistamines (like diphenhydramine or loratadine) can also help relieve discomfort, but please ensure you're not allergic to these medications.
  4. Hydrate and Rest:

    • Stay well-hydrated and ensure you get enough rest; both are important in your body's healing process.
  5. Document Your Observations:

    • Consider keeping a record of when you notice changes in the rash and any new symptoms. This information will be useful if you need to seek medical advice in the future.
  6. Let Knowing Symptoms Guide You:

    • If you notice worsening symptoms, such as severe swelling, persistent pain, or if any respiratory problems develop, seek professional medical advice immediately, as these could signal a more serious allergic reaction.

Lastly, consider discussing your concerns about possible allergies with a healthcare provider for further evaluation, particularly regarding your sensitivity to penicillin and any other medications you might take in the future. Your health and peace of mind are important, and I hope you feel better soon!

Related Questions

Is It Possible to Develop Allergies in Adulthood?

The concept of developing allergies later in life has been on my mind. A young woman I know, who is 22 years old, had no issues being near cats in her childhood. However, as she matured, she started exhibiting allergic reactions. Additionally, she used to enjoy strawberries without any problems, but recently she experienced swelling in her mouth after consuming a handful of them. To give you a bit of context, she stands at about 156 centimeters tall and weighs around 50 kilograms. It's noteworthy that she doesn't partake in alcohol, smoking, or any recreational drugs.

HivesAnaphylaxisPet Allergies
Male25-34
8 minutes ago

Unexplained Urticaria Episodes

A 28-year-old woman, measuring 158 cm and weighing 72 kg, has been experiencing episodes of urticaria for the past month without any obvious cause. The issue began following a localized reaction to her migraine treatment, particularly the medication erenumab. Generally, she has minor reactions to this injection; however, the last two doses have led to significant flare-ups. Subsequently, she began to notice hives appearing sporadically, primarily without identifiable triggers. These episodes tend to intensify during the night but usually subside after taking cetirizine, an antihistamine. Additionally, she has known drug allergies to ciprofloxacin and penicillin. Recently, after taking cefpodoxime, she developed a rash within a few hours, although cefixime did not provoke any adverse reactions.

Drug AllergiesHivesAllergy & Immunology
Male25-34
18 minutes ago

Rash on the Dorsal Side of My Hands

A 24-year-old male, standing 5'3" and weighing 125 pounds, is not currently taking any medications. While I do not smoke, I am often exposed to secondhand smoke from those around me, and I have recently spent time in an environment where a significant amount of unpleasant smoke is produced due to casting activities. For approximately three weeks, I have been experiencing a rash on the backs of both my hands. I initially became aware of it after working on my car's engine. The rash has led to dryness and itching, and I took a photo after my shower today, highlighting the redness that has become particularly noticeable. What are some effective treatments for this condition?

Skin AllergiesAllergy & ImmunologyDermatology
Male25-34
7 hours ago

Understanding Symptoms of Salmonella: What to Do Next

My boyfriend, who is 26, experienced a fever that peaked at approximately 99.5°F yesterday morning. Thankfully, after resting and taking NyQuil, his fever subsided by this morning. However, he has been dealing with severe abdominal pain and persistent diarrhea since last evening, which has not shown much improvement. He has been making frequent trips to the restroom, nearly every hour throughout the night and again today. While I initially thought he might be improving since the fever has decreased, I became alarmed upon noticing bright red blood in his stool and on the toilet paper after he wipes. It has been around 40 hours since the fever began, and my concern has heightened now that blood has appeared. I’ve come across some online information suggesting these symptoms might be typical for salmonella infections, and I’m uncertain whether we should seek medical attention immediately or if it’s advisable to wait another day or two to see if his condition improves. I realize that consulting a doctor as soon as possible would be the best course of action. However, he currently lacks insurance, which makes him hesitant to get checked right away. Any guidance on this matter would be greatly appreciated, thank you.

Drug AllergiesHivesAllergy & Immunology
Male25-34
9 hours ago

Navigating Alcohol Challenges

My partner has recently developed issues with alcohol. Over the past year, he has been consuming significant amounts—roughly two bottles of distilled spirits each week, in addition to beer. A decade ago, he struggled with inhalants and even faced near-fatal consequences, but he had maintained sobriety until he turned to drinking. He believes he has plenty of time before the effects of alcohol will manifest. How long can he continue this way before it becomes a serious problem? He is a 53-year-old male, weighing 325 pounds, standing at 5 feet 11 inches, and he is currently on medication for hypertension. Although we plan to separate later this year, it’s clear that this situation will have an impact on our three children.

Drug AllergiesAsthmaAllergy & Immunology
Male25-34
10 hours ago