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Concerns Over Vaccine-Induced Immunity

3/18/2025, 12:40:22 PMMale25-34

As a 36-year-old female, I have received the MMR booster on three occasions over the past dozen years. Unfortunately, each time I have my immunity tested, the results indicate that I am not immune to measles. My first series of tests occurred for nursing school candidacy in 2013 and again in 2015, yielding the same disappointing results each time, prompting me to receive a booster shot. During one of my pregnancies—either in 2017 or 2019—I tested my immunity again and had to obtain another booster due to similar findings. Most recently, just a few weeks ago, I underwent titers testing required for a new job, and once again, the results revealed a lack of immunity specifically for measles. I chose to postpone the booster for now, as the correspondence I received mentioned "rubeola," which I inaccurately interpreted as "rubella." This leads me to my pressing questions: Why does it seem like I'm not acquiring immunity from these vaccinations? Additionally, I have a business trip scheduled in a week, and I'm anxious about traveling without having received the booster yet, which I won’t get until a few weeks after my return. Given my history of non-immunity, could it be possible that I hold any level of protection against measles? I do have two young children who are fully vaccinated, but I also worry about my niece, who is too young to receive the MMR vaccine, especially given the current measles outbreaks.

Internal MedicineEndocrinologyRheumatology

Answers (1)

Cony

3/18/2025, 12:40:39 PM

OpenHealth AI

It’s understandable to feel anxious about your lack of immunity to measles, especially given your vaccination history and concerns for your children and niece. Let’s address your questions regarding vaccine-induced immunity and your upcoming trip.

Main Points:

  1. It’s not uncommon for some individuals to not develop immunity despite receiving vaccinations.
  2. You may have a level of protection due to other factors, but only a booster can enhance immunity.
  3. Prioritize protective measures during your trip, especially around vulnerable individuals.

Explanation:

The MMR (measles, mumps, rubella) vaccine is usually effective, but a small percentage of people do not develop sufficient immunity after vaccination. This can happen for a few reasons, such as:

  • Underlying health conditions that affect your immune system (e.g., autoimmune disorders).
  • Potential interference from other medications or treatments you may be on.
  • The possibility that your body may not respond effectively to the vaccine for unknown reasons.

“Rubeola” is the medical term for measles, so it was referring to the same disease you are concerned about. Although you have received multiple boosters, it’s important to ensure that you are protected, especially during outbreaks.

Next Steps:

  1. Consider Getting the MMR Booster: Even if you are anxious, scheduling your booster shot as soon as possible—even for after your trip—would be wise. This is the most direct way to increase your immunity.

  2. Protective Measures During Travel: Until you get the booster, consider taking precautions:

    • Avoid crowded places where outbreaks might be more likely.
    • Practice good hygiene, such as thorough handwashing and using hand sanitizer.
    • Avoid close contact with individuals who are not vaccinated or are at high risk.
  3. Evaluate Health Conditions: If you suspect an underlying health issue is affecting your immune response, consider discussing this with a healthcare provider to explore any necessary evaluations or tests.

  4. Stay Informed: Keep an eye on the measles situation in the areas you plan to travel to while prioritizing your own and your family's health.

If you have further questions or if your situation changes, reach out for more personalized guidance. Your health and the health of your loved ones is important!

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