Understanding My Lupus Anticoagulant Test Results
Recently, I underwent a lupus anticoagulant test after experiencing a miscarriage in my second trimester, followed by thrombophlebitis in my arm, where I had an IV. As a result of the clotting issue, I was prescribed Eliquis, which unfortunately led to significant postpartum hemorrhaging, requiring a blood transfusion. I was taken off Eliquis, and by the time of this test, I had not been on it for a week. I’m seeking clarification on my test results, particularly regarding the presence of factor inhibitors. Could this indicate that I have a bleeding disorder? Here are my test result specifics: - **PTT Lupus Anticoagulant:** 39.6 sec (Normal Range: 0-43.5 sec) - **Result:** Normal - **Dilute Prothrombin Time:** 37.1 sec (Normal Range: 0-47.6 sec) - **Result:** Normal - **Thrombin Time (DRVW):** 15.6 sec (Normal Range: 0-23 sec) - **Result:** Normal - **Dilute Viper Venom Time:** 48.3 sec (Normal Range: 0-47.0 sec) - **Result:** Elevated - **DPT Confirm Ratio:** 1.25 (Normal Range: 0-1.34) - **Result:** Normal - **DRVVT Mix:** 43.3 sec (Normal Range: 0-40.4 sec) - **Result:** Elevated - **DRVVT/Confirm Ratio:** 1.2 (Normal Range: 0.8-1.2) - **Result:** Normal **Lupus Reflex Interpretation:** "No lupus anticoagulant present. Results suggest the existence of specific inhibitors affecting one or more factors involved in the common coagulation pathway (Factors X, V, II, or fibrinogen)."
Answers (1)
3/17/2025, 12:30:43 PM
OpenHealth AI
It sounds like you're dealing with complicated test results after a challenging medical history, and I understand you’re looking for clarity regarding the presence of factor inhibitors and their implications for your health. Here’s a breakdown of your results and what they might mean for you.
Overview of Your Test Results
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Normal Results:
- PTT Lupus Anticoagulant
- Dilute Prothrombin Time
- Thrombin Time (DRVW)
- DPT Confirm Ratio
- DRVVT/Confirm Ratio
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Elevated Results:
- Dilute Viper Venom Time (DVT)
- DRVVT Mix
The interpretation from your results indicates no lupus anticoagulant is present, which is often associated with increased risk of clotting. However, the elevated DVT and DRVVT Mix suggest that there are specific inhibitors that could be affecting clotting factors involved in coagulation.
What This Might Mean
- No Lupus Anticoagulant: This is reassuring as it indicates you may not have the classical antiphospholipid syndrome.
- Presence of Inhibitors: The elevated results suggest that there are factors in your blood that are interfering with clotting. This doesn’t necessarily mean you have a bleeding disorder, but it highlights that there might be specific challenges in your coagulation pathway.
Next Steps
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Monitor Symptoms: Pay attention to any unusual bleeding or clotting symptoms. If you experience any, note them down and monitor their frequency and severity.
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Avoid Self-Medication: Given your history with anticoagulants like Eliquis, avoid taking any medications without consulting your healthcare provider.
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Stay Hydrated: Maintaining good hydration can support overall health, particularly in individuals with clotting issues.
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Follow-Up Testing: Discuss with your healthcare provider whether further testing or monitoring is advisable based on these results.
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Inform Your Care Team: Ensure that all your healthcare providers are aware of these test results and your history with miscarriages and recent excessive bleeding. This can guide future treatment plans.
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Educate Yourself: Understanding common clotting disorders and their management might help you advocate for your health better. Reliable sources include the CDC and National Blood Clot Alliance websites.
Conclusion
Navigating the complexities of coagulation issues can be overwhelming, but you’re taking important steps by seeking information and clarifying your concerns. Ensuring good communication with your healthcare providers will be key to managing your health moving forward. If you have any further questions or need support, feel free to reach out again.
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